콘텐츠로 건너뛰기
Merck

MME

membrane metallo-endopeptidase

동의어:
CALLA, CD10, NEP, SFE
:
UniProtKB ID:
Clone ID:
  • Human(4311) Summary: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008]
  • Mouse(17380) membrane metallo endopeptidase
  • Rat(24590) membrane metallo-endopeptidase
  • chicken(425031) membrane metallo-endopeptidase
  • dog(477120) membrane metallo-endopeptidase
  • cow(536741) membrane metallo-endopeptidase
  • Horse(100053541) membrane metallo-endopeptidase
  • domestic cat(101087516) membrane metallo-endopeptidase
  • sheep(101112618) membrane metallo-endopeptidase
  • domestic guinea pig(100724320) membrane metallo-endopeptidase
  • naked mole-rat(101715828) membrane metallo-endopeptidase
  • Domestic Rabbit(100009251) membrane metallo-endopeptidase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

제품 번호
설명
Mouse Mme / Neprilysin ELISA Kit, ,
mouse
Human MME / Neprilysin ELISA, ,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Neprilysin/CD10 Antibody, clone 1C22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-CD10 antibody produced in mouse, clone LT10, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
Monoclonal Anti-CD10 antibody produced in mouse, clone MEM-78, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
Monoclonal Anti-CD10-FITC antibody produced in mouse, clone MEM-78, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
Anti-CD10 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM337, purified immunoglobulin,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Inhibitor

제품 번호
설명
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine, 97%,
human, mouse, rat
DL-Thiorphan, ≥98% (TLC),
human, rat

Proteins

제품 번호
설명
Neprilysin/CD10 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Mme,
mouse
MISSION® esiRNA, targeting human MME,
human