์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

MDM2

MDM2 oncogene, E3 ubiquitin protein ligase

๋™์˜์–ด:
ACTFS, HDMX, hdm2
์ข…:
Human MDM2 (4193), Mouse Mdm2 (17246), Rat Mdm2 (314856), Zebrafish mdm2 (30637), dog MDM2 (403693), domestic cat MDM2 (493939), cow MDM2 (540378), Horse MDM2 (100033891), chicken MDM2 (395609), domestic guinea pig Mdm2 (100724684) ...๋”
UniProtKB ID:
Q00987, A6NL51, A8K2S6, Q13226, Q13297, Q13298, Q13299, Q13300
Clone ID:
  • Human(4193) Summary: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
  • Mouse(17246) transformed mouse 3T3 cell double minute 2
  • Rat(314856) p53 E3 ubiquitin protein ligase
  • Zebrafish(30637) transformed 3T3 cell double minute 2 homolog (mouse)
  • dog(403693) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • domestic cat(493939) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • cow(540378) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • Horse(100033891) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • chicken(395609) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • domestic guinea pig(100724684) MDM2 oncogene, E3 ubiquitin protein ligase
  • naked mole-rat(101724821) MDM2 oncogene, E3 ubiquitin protein ligase
  • sheep(101104979) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
RAB1578
Human MDM2 ELISA, for serum, plasma and cell culture supernatants,
์ข…
human

Antibodies

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
์‘์šฉ๋ถ„์•ผ
MABE281
Anti-MDM2 Antibody, clone 2A10, clone 2A10, from mouse,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
immunoprecipitation (IP)
western blot
OP145
Anti-MDM2 (Ab-5) Mouse mAb (4B2C1.11), liquid, clone 4B2C1.11, Calbiochemยฎ,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
MABE340
Anti-MDM2 Antibody, clone IF2, clone IF2, from mouse,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
western blot
SAB4503937
Anti-phospho-MDM2 (pSer166) antibody produced in rabbit, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse, rat
์‘์šฉ๋ถ„์•ผ
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2500625
Anti-MDM2 (Isoform) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
canine, cat, human
์‘์šฉ๋ถ„์•ผ
ELISA
western blot

Proteins

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
SRP2095
MDM2, HIS tagged human, recombinant, expressed in E. coli, โ‰ฅ80% (SDS-PAGE), buffered aqueous solution,
์ข…
human
M0321
MDM2, GST-tagged human, recombinant, expressed in E. coli, buffered aqueous glycerol solution, โ‰ฅ75% (SDS-PAGE),
์ข…
human

esiRNA

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
EHU098571
MISSIONยฎ esiRNA, targeting human MDM2,
์ข…
human
EMU026991
MISSIONยฎ esiRNA, targeting mouse Mdm2,
์ข…
mouse