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Merck

LPIN1

lipin 1

동의어:
PAP1
종:
UniProtKB ID:
Clone ID:
  • Human(23175) Summary: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
  • Mouse(14245) lipin 1
  • Rat(313977) lipin 1
  • Zebrafish(799099) lipin 1
  • dog(475670) lipin 1
  • Horse(100072273) lipin 1
  • cow(537224) lipin 1
  • domestic cat(101085623) lipin 1
  • chicken(421945) lipin 1
  • sheep(101120647) lipin 1
  • domestic guinea pig(100718634) lipin 1
  • Domestic Rabbit(100346262) lipin 1
  • naked mole-rat(101721483) lipin 1

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Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-LPIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-LPIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Anti-Lipin 1 Antibody, clone 4Y2U3, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
western blot
Monoclonal Anti-LPIN1, (C-terminal) antibody produced in mouse, clone 3D9, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-LPIN1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, horse, human, mouse, rabbit, rat
응용분야
immunohistochemistry
western blot

esiRNA

Product Number
설명
MISSION® esiRNA, targeting mouse Lpin1,
mouse
MISSION® esiRNA, targeting human LPIN1,
human