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Merck

LCK

lymphocyte-specific protein tyrosine kinase

동의어:
LSK, YT16, p56lck, pp58lck
:
UniProtKB ID:
Clone ID:
  • Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
  • Mouse(16818) lymphocyte protein tyrosine kinase
  • Rat(313050) lymphocyte-specific protein tyrosine kinase
  • sheep(100216439) lymphocyte-specific protein tyrosine kinase
  • Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
  • domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
  • naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
  • Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
  • cow(508890) lymphocyte-specific protein tyrosine kinase
  • Horse(100146139) lymphocyte-specific protein tyrosine kinase
  • domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
  • dog(478151) lymphocyte-specific protein tyrosine kinase
  • chicken(396460) lymphocyte-specific protein tyrosine kinase

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ELISA

제품 번호
설명
Phosphotyrosine LCK / Tyrosine-protein Kinase Lck ELISA Kit, ,
human

Small Molecule - Antagonist

제품 번호
설명
Rosmarinic acid, 96%,
human
α-Sexithiophene, ,
human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
ANTI-LCK antibody produced in mouse, clone 8B10, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Monoclonal Anti-LCK antibody produced in mouse, clone LCK-01,
종별 반응성
human
응용분야
flow cytometry
Anti-LCK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, canine, human, mouse, pig, rat
응용분야
ELISA
western blot
Monoclonal Anti-LCK antibody produced in mouse, clone 3F7-F5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunoprecipitation (IP)

western blot
Anti-Lck Antibody, clone 2B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
1-Naphthalenesulfonic acid, >50%,
human
1-Naphthyl phosphate, 99%,
human
2-Naphthalenesulfonic acid, technical grade, 70%,
human
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
human
Pazopanib, ,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Lck,
mouse
MISSION® esiRNA, targeting human LCK,
human