ITCH
itchy E3 ubiquitin protein ligase
동의어:
AIF4, AIP4, NAPP1, dJ468O1.1
종:
Human ITCH (83737), Mouse Itch (16396), Rat Itch (311567), Zebrafish itch (100331274), chicken ITCH (419145), cow ITCH (508431), Horse ITCH (100069340), domestic cat ITCH (101086133), dog ITCH (477199), sheep ITCH (101118041) ...더
UniProtKB ID:
Clone ID:
- Human(83737) Summary: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
- Mouse(16396) itchy, E3 ubiquitin protein ligase
- Rat(311567) itchy E3 ubiquitin protein ligase
- Zebrafish(100331274) itchy E3 ubiquitin protein ligase homolog (mouse)
- chicken(419145) itchy E3 ubiquitin protein ligase
- cow(508431) itchy E3 ubiquitin protein ligase homolog (mouse)
- Horse(100069340) itchy E3 ubiquitin protein ligase
- domestic cat(101086133) itchy E3 ubiquitin protein ligase
- dog(477199) itchy E3 ubiquitin protein ligase
- sheep(101118041) itchy E3 ubiquitin protein ligase
- domestic guinea pig(100724288) itchy E3 ubiquitin protein ligase
- naked mole-rat(101711522) itchy E3 ubiquitin protein ligase
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Antibodies
Product Number
설명
종별 반응성
응용분야
Anti-phospho-ITCH (pT222) Antibody, Chemicon®, from rabbit,
종별 반응성
human
응용분야
dot blot
western blot
western blot
Anti-ITCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
western blot
western blot
Anti- ITCH antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti- ITCH antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-ITCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry