콘텐츠로 건너뛰기
Merck

IL6R

interleukin 6 receptor

동의어:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
종:
UniProtKB ID:
Clone ID:
  • Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
  • Rat(24499) interleukin 6 receptor
  • Zebrafish(100135755) interleukin 6 receptor
  • cow(507359) interleukin 6 receptor
  • domestic cat(101085689) interleukin 6 receptor
  • dog(612271) interleukin 6 receptor
  • domestic guinea pig(100730490) interleukin 6 receptor
  • naked mole-rat(101704925) interleukin 6 receptor
  • sheep(101103369) interleukin 6 receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse,
종별 반응성
human
응용분야
ELISA
flow cytometry

immunohistochemistry

immunoprecipitation (IP)
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-IL-6R Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

Proteins

제품 번호
설명
sIL-6 Receptor alpha human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human IL6R,
human