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Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

동의어:
CLMF, IL-12A, NFSK, NKSF1, P35
:
UniProtKB ID:
Clone ID:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • Zebrafish(445410) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic guinea pig(100379543) interleukin 12a
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

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ELISA

제품 번호
설명
Porcine IL12A / IL12B ELISA Kit, ,
Rhesus Macaque IL12A / IL12B ELISA Kit, ,

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
종별 반응성
human
응용분야
neutralization
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
종별 반응성
mouse
응용분야
neutralization
western blot
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
응용분야
affinity binding assay
flow cytometry

western blot

Proteins

제품 번호
설명
IL-35 (mouse): FC (human), recombinant, expressed in CHO cells,
mouse

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human IL12A,
human
MISSION® esiRNA, targeting mouse Il12a,
mouse