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Merck

GCDH

glutaryl-CoA dehydrogenase

동의어:
ACAD5, GCD
:
UniProtKB ID:
Clone ID:
  • Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
  • Mouse(270076) glutaryl-Coenzyme A dehydrogenase
  • Rat(364975) glutaryl-CoA dehydrogenase
  • Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
  • cow(506310) glutaryl-CoA dehydrogenase
  • Horse(100063310) glutaryl-CoA dehydrogenase
  • domestic cat(101086880) glutaryl-CoA dehydrogenase
  • chicken(771098) glutaryl-CoA dehydrogenase
  • dog(476696) glutaryl-CoA dehydrogenase
  • sheep(101122190) glutaryl-CoA dehydrogenase
  • Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
  • naked mole-rat(101718348) glutaryl-CoA dehydrogenase
  • domestic guinea pig(100714939) glutaryl-CoA dehydrogenase

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Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-GCDH antibody produced in rabbit, affinity isolated antibody,
종별 반응성
guinea pig, human, mouse, rabbit, rat
응용분야
western blot
Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
dog, horse, human, mouse, pig, rabbit, rat
응용분야
immunohistochemistry
western blot

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human GCDH,
human
MISSION® esiRNA, targeting mouse Gcdh,
mouse