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Merck

ERCC2

excision repair cross-complementing rodent repair deficiency, complementation group 2

동의어:
COFS2, EM9, TTD, XPD
:
UniProtKB ID:
Clone ID:
  • Human(2068) Summary: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(13871) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • Rat(308415) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • domestic guinea pig(100721308) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • naked mole-rat(101697378) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • sheep(101116341) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • Domestic Rabbit(100347957) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • Zebrafish(393900) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • cow(100125238) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • domestic cat(101095702) excision repair cross-complementing rodent repair deficiency, complementation group 2
  • dog(493995) excision repair cross-complementing rodent repair deficiency, complementation group 2

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Monoclonal Anti-ERCC2 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence
Anti-ERCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence

Proteins

제품 번호
설명
TFIIH, native complex human, ≥75% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Ercc2,
mouse
MISSION® esiRNA, targeting human ERCC2,
human