콘텐츠로 건너뛰기
Merck

EGFR

epidermal growth factor receptor

동의어:
ERBB, ERBB1, HER1, PIG61, mENA
:
UniProtKB ID:
Clone ID:
  • Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(13649) epidermal growth factor receptor
  • Rat(24329) epidermal growth factor receptor
  • fruit fly(37455) Epidermal growth factor receptor
  • cow(407217) epidermal growth factor receptor
  • Horse(100067755) epidermal growth factor receptor
  • domestic cat(100510799) epidermal growth factor receptor
  • dog(404306) epidermal growth factor receptor
  • chicken(396494) epidermal growth factor receptor
  • domestic guinea pig(100725363) epidermal growth factor receptor
  • naked mole-rat(101723771) epidermal growth factor receptor
  • sheep(780479) epidermal growth factor receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

제품 번호
설명
Phospho-EGFR (pTyr992) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr992) and pan-egfr in cell and tissue lysates,
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr992) in cultured cell lines, 96 assays,
human
Cell-Based phospho-EGFR ELISA Sampler Kit, for detecting phospho-egfr(pTyr845), phospho-egfr(pTyr992), phospho-egfr(pTyr1068) and phospho-egfr in cultured cell lines,
human
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr1068) in cultured cell lines, 96 assays,
human

Small Molecule - Antagonist

제품 번호
설명
Tyrphostin AG 1478, ≥98%,
human, mouse
SU 5416, ≥98% (HPLC),
human, mouse
Genistein, from Glycine max (soybean), ~98% (HPLC),
mouse, human, rat
Genistein, synthetic, ≥98% (HPLC), powder,
mouse, human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-EGFR PE produced in mouse, ,
종별 반응성
horse
응용분야
flow cytometry
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
종별 반응성
human
응용분야
ELISA
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-EGF Receptor antibody, Mouse monoclonal, clone 225, purified from hybridoma cell culture,
종별 반응성
human
응용분야
immunoprecipitation (IP)
Anti-phospho-EGFR (pThr693) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-phospho-EGFR (pTyr1069) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Inhibitor

제품 번호
설명
DAPH, ≥98% (HPLC), solid,
human
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Erlotinib hydrochloride, ,
human
Gefitinib, European Pharmacopoeia (EP) Reference Standard,
human
PKI-166, ≥98% (HPLC),
human

Proteins

제품 번호
설명
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
human
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
human
EGFR (D746-750 T790M C797S), Active, PRECISIO® Kinase, recombinant,
human
EGFR (C797S), Active, recombinant,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Egfr,
mouse
MISSION® esiRNA, targeting human EGFR,
human