DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
동의어:
DFF-45, DFF1, ICAD
종:
Human DFFA (1676), Mouse Dffa (13347), Rat Dffa (114214), Zebrafish dffa (436904), cow DFFA (507981), domestic cat DFFA (101096745), dog DFFA (487449), chicken DFFA (419451), domestic guinea pig Dffa (100719233), naked mole-rat Dffa (101700734)
UniProtKB ID:
Clone ID:
- Human(1676) Summary: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13347) DNA fragmentation factor, alpha subunit
- Rat(114214) DNA fragmentation factor, alpha subunit
- Zebrafish(436904) DNA fragmentation factor, alpha polypeptide
- cow(507981) DNA fragmentation factor, 45kDa, alpha polypeptide
- domestic cat(101096745) DNA fragmentation factor, 45kDa, alpha polypeptide
- dog(487449) DNA fragmentation factor, 45kDa, alpha polypeptide
- chicken(419451) DNA fragmentation factor, 45kDa, alpha polypeptide
- domestic guinea pig(100719233) DNA fragmentation factor, 45kDa, alpha polypeptide
- naked mole-rat(101700734) DNA fragmentation factor, 45kDa, alpha polypeptide
- sheep(101114715) DNA fragmentation factor, 45kDa, alpha polypeptide
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-DFFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-DFFA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
western blot
Anti-DFFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
종별 반응성
human
응용분야
immunohistochemistry
Anti-DFFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-DFFA antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
western blot