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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

๋™์˜์–ด:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
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UniProtKB ID:
Clone ID:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1

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ELISA

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Human DDR1 ELISA, for serum, plasma and cell culture supernatants,
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human

Antibodies

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Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
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human, mouse, rat
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ELISA
immunohistochemistry

western blot
Monoclonal Anti-CD167a antibody produced in mouse, clone 51D6,
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human
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flow cytometry
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
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human
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immunohistochemistry
western blot
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAbยฎ Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
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bovine, human, monkey, mouse, porcine, rat
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affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
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bovine, dog, horse, human, monkey, pig
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immunohistochemistry

Proteins

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DDR1 (444-end), active, GST tagged human, PRECISIOยฎ Kinase, recombinant, expressed in baculovirus infected Sf9 cells, โ‰ฅ70% (SDS-PAGE), buffered aqueous glycerol solution,
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human

esiRNA

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MISSIONยฎ esiRNA, targeting mouse Ddr1,
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mouse
MISSIONยฎ esiRNA, targeting human DDR1,
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human