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Merck

DCTN2

dynactin 2 (p50)

동의어:
DCTN50, DYNAMITIN, RBP50
:
UniProtKB ID:
Clone ID:
  • Human(10540) Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(69654) dynactin 2
  • Rat(299850) dynactin 2 (p50)
  • Zebrafish(394141) dynactin 2 (p50)
  • cow(527201) dynactin 2 (p50)
  • Horse(100050464) dynactin 2 (p50)
  • domestic cat(101093950) dynactin 2 (p50)
  • dog(474415) dynactin 2 (p50)
  • chicken(395587) dynactin 2 (p50)
  • naked mole-rat(101713049) dynactin 2 (p50)
  • domestic guinea pig(100721002) dynactin 2 (p50)
  • sheep(101119807) dynactin 2 (p50)
  • Domestic Rabbit(100339187) dynactin 2 (p50)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-DCTN2 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-DCTN2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Dctn2,
mouse
MISSION® esiRNA, targeting human DCTN2,
human