CTSC
cathepsin C
동의어:
CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS
종:
Human CTSC (1075), Mouse Ctsc (13032), Rat Ctsc (25423), Zebrafish ctsc (368704), domestic cat CTSC (101092140), dog CTSC (403458), cow CTSC (352958), chicken CTSC (419014), sheep CTSC (101112686), domestic guinea pig Ctsc (100714387)
UniProtKB ID:
Clone ID:
- Human(1075) Summary: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13032) cathepsin C
- Rat(25423) cathepsin C
- Zebrafish(368704) cathepsin C
- domestic cat(101092140) cathepsin C
- dog(403458) cathepsin C
- cow(352958) cathepsin C
- chicken(419014) cathepsin C
- sheep(101112686) cathepsin C
- domestic guinea pig(100714387) cathepsin C
- naked mole-rat(101697606) cathepsin C
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-CTSC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-Dipeptidyl-peptidase 1 (heavy chain, Cleaved-Arg394) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
western blot
Anti-CTSC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Proteins
제품 번호
설명
종