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Merck

CLDN8

claudin 8

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(9073) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]
  • Mouse(54420) claudin 8
  • Rat(304124) claudin 8
  • Zebrafish(445278) claudin 8
  • chicken(427974) claudin 8
  • dog(478401) claudin 8
  • domestic cat(101096909) claudin 8
  • cow(538761) claudin 8
  • naked mole-rat(101707430) claudin 8
  • domestic guinea pig(100735357) claudin 8
  • sheep(101106811) claudin 8

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CLDN8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-CLDN8 (196-210) antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
human
응용분야
western blot
Anti-CLDN8 antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
human
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CLDN8,
human