CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
동의어:
종:
Human CHRNA2 (1135), Mouse Chrna2 (110902), Rat Chrna2 (170945), chicken CHRNA2 (395607), cow CHRNA2 (531838), domestic cat CHRNA2 (101092104), dog CHRNA2 (486101), sheep CHRNA2 (101107330), domestic guinea pig Chrna2 (100734964), naked mole-rat Chrna2 (101714975)
UniProtKB ID:
Clone ID:
- Human(1135) Summary: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
- Mouse(110902) cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
- Rat(170945) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- chicken(395607) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- cow(531838) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic cat(101092104) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- dog(486101) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- sheep(101107330) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic guinea pig(100734964) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- naked mole-rat(101714975) cholinergic receptor, nicotinic, alpha 2 (neuronal)
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Small Molecule - Agonist
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Small Molecule - Antagonist
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Antibodies
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종별 반응성
응용분야
Anti-CHRNA2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-Chrna2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Small Molecule - Blocker
Small Molecule - Inhibitor
Small Molecule - Ligand
esiRNA
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