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Merck

CHRM1

cholinergic receptor, muscarinic 1

동의어:
HM1, M1, M1R
종:
UniProtKB ID:
Clone ID:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

Product Number
설명
Pilocarpine hydrochloride, phyproof® Reference Substance,
human
Pilocarpine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Pilocarpine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Pilocarpine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human
Pilocarpine nitrate for system suitability, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Antagonist

Product Number
설명
Benztropine mesylate, ≥98% (HPLC),
human
Procyclidine hydrochloride, ,
human
Scopolamine hydrobromide, meets USP testing specifications,
human
(−)-Scopolamine hydrochloride, analytical standard,
human
Quinuclidine, 97%,
rat

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
종별 반응성
mouse, rat
응용분야
immunohistochemistry
western blot
Anti-Muscarinic Acetylcholine Receptor (M1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
종별 반응성
mouse, rat
응용분야
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
설명
Amitriptyline hydrochloride, ≥98% (TLC), powder,
human
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
human
Haloperidol, powder,
human, rat
Harmaline, ≥95%,
human, rat
Clozapine, ,
human, rat

Small Molecule - Ligand

Product Number
설명
Aminobenztropine, solid,
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human CHRM1,
human