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Merck

CDK9

cyclin-dependent kinase 9

동의어:
C-2k, CDC2L4, CTK1, PITALRE, TAK
:
UniProtKB ID:
Clone ID:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • cow(520580) cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9

Custom & Knockdown Gene Products

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Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-CDK9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-Phospho-CDK9-T186 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-CDK9 antibody produced in rabbit, ,
종별 반응성
응용분야
immunohistochemistry
western blot
Rabbit anti-CDK9 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
종별 반응성
human, mouse
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
설명
Flavopiridol hydrochloride hydrate, ≥98% (HPLC), powder,
human
Roscovitine, ≥98% (TLC),
human, mouse, rat
Olomoucine, ≥98% (HPLC),
human, rat

Proteins

Product Number
설명
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
human
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human CDK9,
human