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Merck

CDC27

cell division cycle 27

동의어:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
:
UniProtKB ID:
Clone ID:
  • Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(217232) cell division cycle 27
  • Rat(360643) cell division cycle 27
  • Zebrafish(30450) cell division cycle 27
  • cow(540660) cell division cycle 27 homolog (S. cerevisiae)
  • Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
  • chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
  • domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
  • dog(490924) cell division cycle 27 homolog (S. cerevisiae)
  • fruit fly(38798) CG8610 gene product from transcript CG8610-RB
  • sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)
  • domestic guinea pig(100731091) cell division cycle 27
  • naked mole-rat(101717421) cell division cycle 27

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CDC27 Antibody, clone 7U5A3, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
western blot
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-H-NUC antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-APC3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Cdc27,
mouse
MISSION® esiRNA, targeting human CDC27,
human