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Merck

CACNA1F

calcium channel, voltage-dependent, L type, alpha 1F subunit

동의어:
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
:
UniProtKB ID:
Clone ID:
  • Human(778) Summary: This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq, Feb 2012]
  • Mouse(54652) calcium channel, voltage-dependent, alpha 1F subunit
  • Rat(114493) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • sheep(101104552) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic guinea pig(100720484) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • naked mole-rat(101722090) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • Zebrafish(386662) calcium channel, voltage-dependent, alpha 1F subunit
  • dog(480915) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • cow(509779) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic cat(101080870) calcium channel, voltage-dependent, L type, alpha 1F subunit

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Small Molecule - Allosteric Modulator

제품 번호
설명
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CACNA1F antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Blocker

제품 번호
설명
Amlodipine besylate, ≥98% (HPLC),
human
Nicardipine hydrochloride, powder, ≥98%,
human
Diltiazem hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human
(±)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Nifedipine, Pharmaceutical Secondary Standard; Certified Reference Material,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CACNA1F,
human