ATM
ataxia telangiectasia mutated
동의어:
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
종:
Human ATM (472), Mouse Atm (11920), Rat Atm (300711), Zebrafish atm (403064), cow ATM (526824), Horse ATM (100061765), domestic cat ATM (101089291), dog ATM (479450), chicken ATM (395401), Thale Cress ATM (823975) ...더
UniProtKB ID:
Clone ID:
- Human(472) Summary: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
- Mouse(11920) ataxia telangiectasia mutated homolog (human)
- Rat(300711) ataxia telangiectasia mutated
- Zebrafish(403064) ataxia telangiectasia mutated
- cow(526824) ataxia telangiectasia mutated
- Horse(100061765) ataxia telangiectasia mutated
- domestic cat(101089291) ataxia telangiectasia mutated
- dog(479450) ataxia telangiectasia mutated
- chicken(395401) ataxia telangiectasia mutated
- Thale Cress(823975) serine/threonine-protein kinase ATM
- naked mole-rat(101718948) ataxia telangiectasia mutated
- domestic guinea pig(100717983) ataxia telangiectasia mutated
- sheep(101105847) ataxia telangiectasia mutated
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-p-ATM (Ser1981) Antibody, clone 1E19, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
affinity binding assay
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate, clone 10H11.E12, from mouse, PE,
종별 반응성
human, mouse, rat
응용분야
flow cytometry
Anti-ATM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-ATM Antibody, clone AM9, ascites fluid, clone AM9, Upstate®,
종별 반응성
human
응용분야
western blot
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP224, recombinant, expressed in proprietary host, affinity isolated antibody,
종별 반응성
human, mouse, pig
응용분야
flow cytometry
immunohistochemistry
immunohistochemistry
Proteins
제품 번호
설명
종