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Merck

APRT

adenine phosphoribosyltransferase

๋™์˜์–ด:
AMP, APRTD
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UniProtKB ID:
Clone ID:
  • Human(353) Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11821) adenine phosphoribosyl transferase
  • Rat(292072) adenine phosphoribosyl transferase
  • Zebrafish(393641) adenine phosphoribosyl transferase
  • chicken(100857155) adenine phosphoribosyltransferase
  • dog(479615) adenine phosphoribosyltransferase
  • domestic cat(101098913) adenine phosphoribosyltransferase
  • cow(519017) adenine phosphoribosyltransferase
  • fruit fly(48224) Adenine phosphoribosyltransferase
  • domestic guinea pig(100731502) adenine phosphoribosyltransferase
  • naked mole-rat(101713665) adenine phosphoribosyltransferase
  • sheep(101108335) adenine phosphoribosyltransferase

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Antibodies

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Anti-APRT antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
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human
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immunofluorescence
immunohistochemistry

western blot

esiRNA

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MISSIONยฎ esiRNA, targeting human APRT,
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human
MISSIONยฎ esiRNA, targeting mouse Aprt,
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mouse