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Merck

ANTXR1

anthrax toxin receptor 1

동의어:
ATR, GAPO, TEM8
:
UniProtKB ID:
Clone ID:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Phospho-ANTXR1-pY425 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
dot blot
Anti-ATR (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-TEM8/Anthrax Toxin Receptor 1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Phospho-ANTXR1-pY382 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
dot blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human ANTXR1,
human
MISSION® esiRNA, targeting mouse Antxr1,
mouse