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Merck

ANGPTL4

angiopoietin-like 4

동의어:
ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158
:
UniProtKB ID:
Clone ID:
  • Human(51129) Summary: This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Jul 2008]
  • Mouse(57875) angiopoietin-like 4
  • Rat(362850) angiopoietin-like 4
  • naked mole-rat(101718658) angiopoietin-like 4
  • domestic guinea pig(100733453) angiopoietin-like 4
  • Goat(100860916) angiopoietin-like 4
  • sheep(101104317) angiopoietin-like 4
  • Zebrafish(492647) angiopoietin-like 4
  • domestic cat(101090747) angiopoietin-like 4
  • cow(509963) angiopoietin-like 4
  • dog(476724) angiopoietin-like 4
  • chicken(769087) angiopoietin-like 4

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-ANGPTL4, (C-terminal) antibody produced in mouse, clone 1A12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunoprecipitation (IP)
Anti-ANGPTL4 (MID) Antibody, clone ZMD.521, Chemicon®, from rabbit,
종별 반응성
human, mouse, rat
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human ANGPTL4,
human
MISSION® esiRNA, targeting mouse Angptl4,
mouse