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  • Tuning the keto equilibrium in 4-substituted dipicolinic acid derivatives.

Tuning the keto equilibrium in 4-substituted dipicolinic acid derivatives.

Organic & biomolecular chemistry (2003-08-22)
Anne-Sophie Chauvin, Sandrine Gras, Jean-Claude G Bünzli
ABSTRACT

The synthesis of 4-substituted dipicolinic acid derivatives requiring palladium catalysis is described. A keto-enol equilibrium has been observed, depending on the nature of the 2,6-position substituents.

MATERIALS
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Product Description

Sigma-Aldrich
Chelidamic acid hydrate, ≥97.0% (dried material, T), ~1 mol/mol water