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Key Documents

SML3624

Sigma-Aldrich

Cefditoren pivoxil

≥98% (HPLC)

Synonym(s):

(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester, CCRIS 7768, ME 1207

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About This Item

Empirical Formula (Hill Notation):
C25H28N6O7S3
CAS Number:
117467-28-4
Molecular Weight:
620.72
UNSPSC Code:
51111800
UNSPSC Code:
12352200
NACRES:
NA.25

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

Biochem/physiol Actions

Cefditoren pivoxil is a prodrug of an orally available, broad spectrum third-generation cephalosporin antibiotic Cefditoren. It is active against both gram-negative and gram-positive bacteria. Cefditoren pivoxil is used for treatment of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Taiga Miyazaki et al.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 25(9), 702-707 (2019-04-16)
Oral antibiotic therapy for patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) usually involves an aminopenicillin with clavulanic acid, a macrolide, or a quinolone. To date, however, the clinical efficacy and safety of the oral cephalosporin cefditoren pivoxil

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