IAK0108
Phagocytosis Assay Kit
Green Zymosan, sufficient for 100 fluorometric assays
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About This Item
UNSPSC Code:
12352207
NACRES:
NA.84
Recommended Products
suitability
suitable for fluorescence
storage temp.
2-8°C
General description
Phagocytosis is a cellular process for ingesting and eliminating microorganisms, foreign substances, and apoptotic cells. It is a specific form of endocytosis initiated by recognition and binding of foreign particles by cell surface receptors, followed by their engulfment, and formation of phagosomes. Maturing phagosomes transform to phagolysosomes which destroy the pathogen through enzymes and toxic peroxides. Zymosan prepared from yeast cell wall (Saccharomyces cerevisiae) and consisting of protein-carbohydrate complexes is frequently used as a pathogen in phagocytosis assays.
Application
The Phagocytosis Assay Kit (Green Zymosan) uses fluorescently pre-labeled Zymosan particles to detect and quantify in vitro phagocytosis by fluorescent microscope, spectrophotometer (Ex/Em = 490/520 nm) or flow cytometry.
Suitability
This kit is suitable for screening activators and/or inhibitors of phagocytosis and Toll-like receptor ligands (TLR) in mammalian cells.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 1B
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Certificates of Analysis (COA)
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