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Merck

UBA3

ubiquitin-like modifier activating enzyme 3

Synonyms:
UBE1C, hUBA3
Species:
Human UBA3 (9039), Mouse Uba3 (22200), Rat Uba3 (117553), fruit fly Uba3 (36539), Zebrafish uba3 (406776), Horse UBA3 (100053395), domestic cat UBA3 (101090175), dog UBA3 (476560), chicken UBA3 (426073), domestic guinea pig Uba3 (100720892) ...More
UniProtKB ID:
Q8TBC4, A6NLB5, A8K027, O76088, Q9NTU3
Gene ID:
  • Human(9039) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(22200) ubiquitin-like modifier activating enzyme 3
  • Rat(117553) ubiquitin-like modifier activating enzyme 3
  • fruit fly(36539) Ubiquitin activating enzyme 3
  • Zebrafish(406776) ubiquitin-like modifier activating enzyme 3
  • Horse(100053395) ubiquitin-like modifier activating enzyme 3
  • domestic cat(101090175) ubiquitin-like modifier activating enzyme 3
  • dog(476560) ubiquitin-like modifier activating enzyme 3
  • chicken(426073) ubiquitin-like modifier activating enzyme 3
  • domestic guinea pig(100720892) ubiquitin-like modifier activating enzyme 3
  • naked mole-rat(101716749) ubiquitin-like modifier activating enzyme 3
  • Domestic Rabbit(100343309) ubiquitin-like modifier activating enzyme 3
  • cow(512647) ubiquitin-like modifier activating enzyme 3
  • sheep(101116609) ubiquitin-like modifier activating enzyme 3

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2103515
Anti-UBA3, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
HPA034874
Anti-UBA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA034873
Anti-UBA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
HPA065335
Anti-UBA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU083231
MISSION® esiRNA, targeting human UBA3,
Species
human
EMU054691
MISSION® esiRNA, targeting mouse Uba3,
Species
mouse