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Merck

PLA2G1B

phospholipase A2, group IB (pancreas)

Synonyms:
PLA2, PLA2A, PPLA2
Species:
Human PLA2G1B (5319), Mouse Pla2g1b (18778), Rat Pla2g1b (29526), cow PLA2G1B (282457), sheep PLA2G1B (101117700), domestic guinea pig Pla2g1b (100732984), naked mole-rat Pla2g1b (101699902), Zebrafish pla2g1b (571738), chicken PLA2G1B (770292), chicken PLA2G1B (416980) ...More
UniProtKB ID:
P04054, B2R4H5, Q3KPI1
Gene ID:
  • Human(5319) Summary: Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]
  • Mouse(18778) phospholipase A2, group IB, pancreas
  • Rat(29526) phospholipase A2, group IB, pancreas
  • cow(282457) phospholipase A2, group IB (pancreas)
  • sheep(101117700) phospholipase A2, group IB (pancreas)
  • domestic guinea pig(100732984) phospholipase A2, group IB (pancreas)
  • naked mole-rat(101699902) phospholipase A2, group IB (pancreas)
  • Zebrafish(571738) phospholipase A2, group IB (pancreas)
  • chicken(770292) phospholipase A2, group IB (pancreas)
  • chicken(416980) phospholipase A2, group IB (pancreas)
  • domestic cat(101095522) phospholipase A2, group IB (pancreas)
  • dog(404011) phospholipase A2, group IB (pancreas)

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA060803
Anti-PLA2G1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB1410970
Anti-PLA2G1B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
HPA047822
Anti-PLA2G1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
A231
Arachidonyl trifluoromethyl ketone, oil, ≥97% (NMR),
Species
human
I7378
Indomethacin, 98.5-100.5% (in accordance with EP),
Species
human, mouse, rat
I8280
Indomethacin, meets USP testing specifications,
Species
human, mouse, rat
594687
α-Sexithiophene, ,
Species
human, rat

Proteins

Product Number
Description
Species
P8913
Phospholipase A2 from bovine pancreas, lyophilized powder, ≥20 units/mg protein,
Species
cow
P6534
Phospholipase A2 from porcine pancreas, ammonium sulfate suspension, ≥600 units/mg protein,
Species

esiRNA

Product Number
Description
Species
EMU048901
MISSION® esiRNA, targeting mouse Pla2g1b,
Species
mouse