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Merck

PKD2

polycystic kidney disease 2 (autosomal dominant)

Synonyms:
APKD2, PC2, PKD4, Pc-2, TRPP2
Species:
Human PKD2 (5311), Mouse Pkd2 (18764), Rat Pkd2 (498328), fruit fly Pkd2 (34651), Zebrafish pkd2 (432387), domestic cat PKD2 (101098948), dog PKD2 (487852), chicken PKD2 (422585), cow PKD2 (530393), sheep PKD2 (101103569) ...More
UniProtKB ID:
Q13563, O60441, Q15764, Q2M1Q3, Q2M1Q5
Gene ID:
  • Human(5311) Summary: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
  • Mouse(18764) polycystic kidney disease 2
  • Rat(498328) polycystic kidney disease 2 (autosomal dominant)
  • fruit fly(34651) Polycystic kidney disease gene-2
  • Zebrafish(432387) polycystic kidney disease 2
  • domestic cat(101098948) polycystic kidney disease 2 (autosomal dominant)
  • dog(487852) polycystic kidney disease 2 (autosomal dominant)
  • chicken(422585) polycystic kidney disease 2 (autosomal dominant)
  • cow(530393) polycystic kidney disease 2 (autosomal dominant)
  • sheep(101103569) polycystic kidney disease 2 (autosomal dominant)
  • domestic guinea pig(100714947) polycystic kidney disease 2 (autosomal dominant)
  • naked mole-rat(101726639) polycystic kidney disease 2 (autosomal dominant)
  • Domestic Rabbit(100008872) polycystic kidney disease 2 (autosomal dominant)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
ST1042
Anti-PKD2 Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human
Application
AB9084
Anti-Polycystin-L Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry
western blot
HPA015794
Anti-PKD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
07-488
Anti-PKD2 Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
AB9088
Anti-Polycystin-2 Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU040961
MISSION® esiRNA, targeting mouse Pkd2,
Species
mouse
EHU029001
MISSION® esiRNA, targeting human PKD2,
Species
human