OSTM1
osteopetrosis associated transmembrane protein 1
- Human(28962) Summary: This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008]
- Mouse(14628) osteopetrosis associated transmembrane protein 1
- Rat(499474) osteopetrosis associated transmembrane protein 1
- Zebrafish(100320445) osteopetrosis associated transmembrane protein 1
- chicken(421773) osteopetrosis associated transmembrane protein 1
- dog(612165) osteopetrosis associated transmembrane protein 1
- domestic cat(101098144) osteopetrosis associated transmembrane protein 1
- cow(518522) osteopetrosis associated transmembrane protein 1
- naked mole-rat(101701537) osteopetrosis associated transmembrane protein 1
- Domestic Rabbit(100328697) osteopetrosis associated transmembrane protein 1
- domestic guinea pig(100712630) osteopetrosis associated transmembrane protein 1
- sheep(101118028) osteopetrosis associated transmembrane protein 1
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