NTRK2
neurotrophic tyrosine kinase, receptor, type 2
Synonyms:
GP145-TrkB, TRKB, trk-B
Species:
Human NTRK2 (4915), Mouse Ntrk2 (18212), Rat Ntrk2 (25054), sheep NTRK2 (101116015), Domestic Rabbit NTRK2 (100352548), naked mole-rat Ntrk2 (101720037), domestic guinea pig Ntrk2 (100723565), chicken NTRK2 (396157), cow NTRK2 (505824), Horse NTRK2 (100061700) ...More
UniProtKB ID:
Gene ID:
- Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
- Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
- sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2
- Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
- naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
- domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
- chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
- cow(505824) neurotrophic tyrosine kinase, receptor, type 2
- Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
- domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
- dog(484147) neurotrophic tyrosine kinase, receptor, type 2
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Custom Gene Products
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NTRK2 antibody produced in mouse, clone 3D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-NTRK2 (pTyr705) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-TrkB Antibody, serum, Chemicon®,
Species Reactivity
mouse, rat
Application
immunohistochemistry
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-TrkB (Tyr816) Antibody, clone 2C21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, mouse, rat, sheep
Application
affinity binding assay
immunocytochemistry
inhibition assay
western blot
immunocytochemistry
inhibition assay
western blot
Proteins
Product Number
Description
Species
TRKB (455-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species