NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Synonyms:
AMDM, ANPRB, ANPb, GUC2B, GUCY2B, NPRB, NPRBi
Species:
Human NPR2 (4882), Mouse Npr2 (230103), Rat Npr2 (116564), chicken NPR2 (100859339), dog NPR2 (474762), Horse NPR2 (100055416), cow NPR2 (281357), domestic cat NPR2 (101094301), Goat NPR2 (100861577), sheep NPR2 (101112950) ...More
UniProtKB ID:
Gene ID:
- Human(4882) Summary: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
- Mouse(230103) natriuretic peptide receptor 2
- Rat(116564) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- chicken(100859339) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- dog(474762) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- Horse(100055416) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- cow(281357) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- domestic cat(101094301) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- Goat(100861577) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- sheep(101112950) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- naked mole-rat(101712380) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
- domestic guinea pig(100732021) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
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