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ITGAV

integrin, alpha V

Synonyms:
CD51, MSK8, VNRA, VTNR
Species:
Human ITGAV (3685), Mouse Itgav (16410), Rat Itgav (296456), sheep ITGAV (443143), Domestic Rabbit ITGAV (100008956), domestic guinea pig Itgav (100728575), naked mole-rat Itgav (101717672), Zebrafish itgav (100151255), cow ITGAV (281875), Horse ITGAV (100068706) ...More
UniProtKB ID:
P06756, A0AV67, B0LPF4, B7Z883, D3DPG8, E7EWZ6, Q53SK4, Q59EB7
Gene ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Description
Species
G1269
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB1976F
Anti-Integrin αVβ3 Antibody, clone LM609, FITC conjugated, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunohistochemistry
MAB1976Z
Anti-Integrin αVβ3 Antibody, clone LM609, Azide Free, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
MAB1876
Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1), clone 27.1 (VNR-1), Chemicon®, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
MAB1976
Anti-Integrin αVβ3 Antibody, clone LM609, clone LM609, Chemicon®, from mouse,
Species Reactivity
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
ZRB1189
Anti-Integrin pan-αV Antibody, clone EM01309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU051281
MISSION® esiRNA, targeting mouse Itgav,
Species
mouse
EHU002301
MISSION® esiRNA, targeting human ITGAV,
Species
human