IL27
interleukin 27
IL-27, IL-27A, IL27A, IL27p28, IL30, p28
Human IL27 (246778), Mouse Il27 (246779), Rat Il27 (365368), domestic cat IL27 (101093822), cow IL27 (614927), dog IL27 (607880), sheep IL27 (101122495), domestic guinea pig Il27 (100724612), naked mole-rat Il27 (101724119)
- Human(246778) Summary: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
- Mouse(246779) interleukin 27
- Rat(365368) interleukin 27
- domestic cat(101093822) interleukin 27
- cow(614927) interleukin 27
- dog(607880) interleukin 27
- sheep(101122495) interleukin 27
- domestic guinea pig(100724612) interleukin 27
- naked mole-rat(101724119) interleukin 27
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