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Merck

DEFA5

defensin, alpha 5, Paneth cell-specific

Synonyms:
DEF5, HD-5
Species:
UniProtKB ID:
Gene ID:
  • Human(1670) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Jul 2008]
  • Mouse(13239) defensin, alpha, 5
  • Rat(286995) defensin, alpha 5, Paneth cell-specific
  • Horse(100307028) defensin, alpha 5, Paneth cell-specific

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DEFA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8, clone 8C8, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-DEFA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DEFA5,
Species
human