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Merck

CSE1L

CSE1 chromosome segregation 1-like (yeast)

Synonyms:
CAS, CSE1, XPO2
Species:
UniProtKB ID:
Gene ID:
  • Human(1434) Summary: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(110750) chromosome segregation 1-like (S. cerevisiae)
  • Rat(362273) CSE1 chromosome segregation 1-like (yeast)
  • Zebrafish(30707) chromosome segregation 1-like (S. cerevisiae)
  • cow(518622) CSE1 chromosome segregation 1-like (yeast)
  • Horse(100056886) CSE1 chromosome segregation 1-like (yeast)
  • domestic cat(101081375) CSE1 chromosome segregation 1-like (yeast)
  • dog(477257) CSE1 chromosome segregation 1-like (yeast)
  • chicken(419212) CSE1 chromosome segregation 1-like (yeast)
  • sheep(101120005) CSE1 chromosome segregation 1-like (yeast)
  • domestic guinea pig(100725108) CSE1 chromosome segregation 1-like (yeast)
  • naked mole-rat(101705453) CSE1 chromosome segregation 1-like (yeast)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CSE1L, (C-terminal) antibody produced in mouse, clone 2C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CSE1L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-CSE1L antibody produced in mouse, clone 1C4, ascites fluid, solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-CSE1L antibody produced in mouse, clone 3F8, ascites fluid, solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-CSE1L antibody produced in mouse, clone 1E4, ascites fluid, solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CSE1L,
Species
human
MISSION® esiRNA, targeting mouse Cse1l,
Species
mouse