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Merck

CDC6

cell division cycle 6

Synonyms:
CDC18L, HsCDC18, HsCDC6
Species:
Human CDC6 (990), Mouse Cdc6 (23834), Rat Cdc6 (360621), naked mole-rat Cdc6 (101724964), domestic guinea pig Cdc6 (100729621), sheep CDC6 (101107536), Domestic Rabbit CDC6 (100357421), Zebrafish cdc6 (402825), Thale Cress CDC6 (817518), dog CDC6 (480527) ...More
UniProtKB ID:
Q99741, Q8TB30
Gene ID:
  • Human(990) Summary: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
  • Mouse(23834) cell division cycle 6
  • Rat(360621) cell division cycle 6
  • naked mole-rat(101724964) cell division cycle 6
  • domestic guinea pig(100729621) cell division cycle 6
  • sheep(101107536) cell division cycle 6 homolog (S. cerevisiae)
  • Domestic Rabbit(100357421) cell division cycle 6 homolog (S. cerevisiae)
  • Zebrafish(402825) cell division cycle 6 homolog (S. cerevisiae)
  • Thale Cress(817518) cell division control 6
  • dog(480527) cell division cycle 6 homolog (S. cerevisiae)
  • cow(515301) cell division cycle 6 homolog (S. cerevisiae)
  • Horse(100067788) cell division cycle 6 homolog (S. cerevisiae)
  • domestic cat(101082791) cell division cycle 6 homolog (S. cerevisiae)
  • fruit fly(38989) CG5971 gene product from transcript CG5971-RA

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4503859
Anti-phospho-CDC6 (pSer54) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB5701916
Anti-Phospho-Cdc6-S54 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
SAB1411704
Anti-CDC6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
proximity ligation assay
western blot
SAB4503728
Anti-CDC6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
SAB4503727
Anti-CDC6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU024851
MISSION® esiRNA, targeting human CDC6,
Species
human
EMU061341
MISSION® esiRNA, targeting mouse Cdc6,
Species
mouse