CBS
cystathionine-beta-synthase
Synonyms:
HIP4
Species:
Human CBS (875), Mouse Cbs (12411), Rat Cbs (24250), naked mole-rat Cbs (101703797), domestic guinea pig Cbs (100734876), sheep CBS (101106301), Domestic Rabbit CBS (100008766), fruit fly Cbs (5657009), cow CBS (514525), domestic cat CBS (101093038) ...More
UniProtKB ID:
Gene ID:
- Human(875) Summary: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]
- Mouse(12411) cystathionine beta-synthase
- Rat(24250) cystathionine beta synthase
- naked mole-rat(101703797) cystathionine-beta-synthase
- domestic guinea pig(100734876) cystathionine-beta-synthase
- sheep(101106301) cystathionine-beta-synthase
- Domestic Rabbit(100008766) cystathionine-beta-synthase
- fruit fly(5657009) Calcium-binding protein in Shaker
- cow(514525) cystathionine-beta-synthase
- domestic cat(101093038) cystathionine-beta-synthase
- dog(611071) cystathionine-beta-synthase
- fruit fly(36492) centrosomin's beautiful sister
- chicken(418545) cystathionine-beta-synthase
- fruit fly(33081) Cystathionine beta-synthase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CBS antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-CBS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-CBS, (N-terminal) antibody produced in mouse, clone 6B8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CBS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-CBS antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot