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Merck

Ethoxyresorufin O-deethylation by human liver microsomes.

British journal of clinical pharmacology (1986-09-01)
F M Williams, E Mutch, K W Woodhouse, D Lambert, M D Rawlins
要旨

As a substrate for human liver microsomes, ethoxyresorufin appears to be metabolised by a group of cytochrome P450 isoenzymes which are inducible by cigarette smoking. Kinetic studies in microsomes from four human livers indicate that only one enzyme component is involved over the full substrate range. Ethoxyresorufin O-deethylation activity at both high and low substrate concentrations correlated with the high affinity component of ethoxycoumarin O-deethylation and of diphenyloxazole metabolism.

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製品内容

Sigma-Aldrich
2,5-ジフェニルオキサゾール, 99%, suitable for scintillation
カタログ番号
容量
在庫状況
単価
数量
Sigma-Aldrich
2,5-ジフェニルオキサゾール, suitable for liquid scintillation spectrometry
カタログ番号
容量
在庫状況
単価
数量