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Merck

New stable backbone linker resins for solid-phase peptide synthesis.

Organic letters (2003-02-14)
Wenxin Gu, Richard B Silverman
要旨

[reaction: see text] Two new 4-methoxybenzaldehyde backbone linker resins were developed for the solid-phase synthesis of peptides. The linkers are very stable during the cleavage of common protecting groups for amines (Fmoc, Boc) and carboxylic acids (Me, All, tBu) in peptide synthesis. Cleavage from the resin with refluxing TFA is sufficiently mild for peptides containing polar and nonpolar amino acids.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
4-メトキシベンズアルデヒド, 98%
カタログ番号
容量
在庫状況
単価
数量
Supelco
p-アニスアルデヒド, analytical standard
カタログ番号
容量
在庫状況
単価
数量