1453049

Naloxone Related Compound D CII

United States Pharmacopeia (USP) Reference Standard

• 別名: (4R, 4aS, 7aR, 12bS)-3-allyl-4a,9-dihydroxy-2,3,4,4a-tetrahydro-1H,4,12- methanobenzofuro[3,2-e]-isoquinolin-7(7aH)-one
• 実験式（ヒル表記法）: C₁₉H₁₉NO₄
• CAS番号: 26451-92-3
• 分子量: 325.36
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• APIファミリー: naloxone
• 包装: pkg of 25 mg
• メーカー／製品名: USP
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C

詳細

詳細

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

アプリケーション

• Interactive effects of opioid and adrenergic-α2 receptor agonists: Research highlights the complex interactions between µ-opioid and adrenergic-α2 receptor agonists in rats, focusing on the primary Kratom alkaloid Mitragynine and its metabolite 7-Hydroxymitragynine. This study is pivotal for understanding the biochemical pathways involved in opioid receptor antagonist research, offering insights into naloxone-related compound applications in opioid addiction and withdrawal management (Hiranita et al., 2022).


• Diels-Alder reactions of morphinan derivatives: The synthesis and transformations of Diels-Alder adducts of morphinan-6,8-dienes are discussed, illuminating the role of naloxone analogs in synthesizing novel opioid receptor antagonists. These findings contribute to the opioid antagonist research, particularly in exploring structural analogs of naloxone for enhanced therapeutic effects (Marton et al., 2022).


• Impact of brain metastases on methylnaltrexone: A post hoc analysis of three randomized studies investigates the influence of brain metastases on the CNS effects of methylnaltrexone. This research underlines the importance of naloxone derivatives in modifying opioid-induced side effects, which is crucial for the development of safer opioid antagonists in supportive cancer care (Brenner et al., 2021).

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

その他情報

Sales restrictions may apply.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable