SRP8027

CD24 (mouse): FC (human)

recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE)

• 別名: M1/69-J11D heat stable antigen, NaMN adenylyltransferase 1, Nectadrin, X62 Heat stable antigen (HSA)
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: mouse
• リコンビナント: expressed in HEK 293 cells
• アッセイ: >90% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: ~50 kDa by SDS-PAGE
• 包装: pkg of 50 μg
• 不純物: <0.06 EU/μg endotoxin, tested
• UniProtアクセッション番号: P24807
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... CD24(100133941)

詳細

詳細

CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns).

物理的形状

凍結乾燥品(PBS)。

再構成

Reconstitute with 50 μL deionized water.

その他情報

Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable