SRP6027

UbcH5b ヒト

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• 別名: UbcH
• CAS番号: 2026618-65-3
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: ≥95% (SDS-PAGE)
• 形状: liquid
• 分子量: 17.0 kDa
• 包装: pkg of 10 μg
• 濃度: ~1.0 mg/mL
• 不純物: Endotoxin, tested
• NCBIアクセッション番号: P62837
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... UB2D2(7322)

詳細

詳細

E2 ubiquitin conjugating enzyme (UbcH5b), also called as ubiquitin conjugating enzyme E2D2 (UBE2D2), belongs to the active class of E2 ubiquitin conjugating enzymes, which also includes UbcH5A and UbcH5C. UbcH5b structure contains four N-terminal α-helices followed by four-stranded antiparallel β-sheet.

生物化学的／生理学的作用

E2 ubiquitin conjugating enzyme (UbcH5b) is a vital component of E3 complex SCFβ-TrCP and it plays an important role in phospho-IκBα ubiquitination. UbcH5b along with others members of active classes of E2 enzymes plays a vital role in degradation of many regulatory and abnormal proteins, including important human transcription factors, such as p53, nuclear factor-κB (NF-κB) and c-Fos.

物理的形状

Supplied at a concentration of 1.0 mg/ml in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable