SRP0697

TAU-316 Protein

recombinant

• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• リコンビナント: expressed in E. coli
• アッセイ: 70-95% (SDS-PAGE)
• 形状: frozen liquid
• 分子量: ~39 kDa
• 濃度: 0.2 μg/μL
• アクセッション番号: P10636-3
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... MAPT(4137)

詳細

アプリケーション

Useful for kinase assay and Western blot.

生物化学的／生理学的作用

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type ⁽¹⁾. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy ⁽²⁾.

シーケンス

Full Length

再構成

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

保管および安定性

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable