SML2616

Bepotastine besilate

≥98% (HPLC)

• 別名: (+)-4-[[(S)-p-chloro-alpha-2­pyridylbenzyl]oxy]-1-piperidine butyric acid monobenzenesulfonate, Bepreve
• 実験式（ヒル表記法）: C₂₁H₂₅ClN₂O₃ · C₆H₆O₃S
• CAS番号: 190786-44-8
• 分子量: 547.06
• MDL番号: MFCD01938491
• UNSPSCコード: 12352200

特性

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 光学活性: [α]/D 4.5 to 6.5°, c = 1 in methanol
• 保管条件: desiccated
• 色: white to beige
• 保管温度: −20°C
• InChI: 1S/C21H25ClN2O3.C6H6O3S/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26;7-10(8,9)6-4-2-1-3-5-6/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26);1-5H,(H,7,8,9)/t21-;/m1./s1
• InChI Key: UDGHXQPQKQPSBB-ZMBIFBSDSA-N

詳細

生物化学的／生理学的作用

Bepotastine besilate is a second generation antihistamine used clinically for the treatment of itching associated with allergic conjunctivitis, allergic rhinitis and urticaria/pruritus. It is a direct H1-receptor antagonist that inhibits the release of histamine from mast cells.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Warning
• 危険有害性情報: H361d
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable