SML0286

BMS 753

≥98% (HPLC)

• 別名: 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid
• 実験式（ヒル表記法）: C₂₁H₂₁NO₄
• CAS番号: 215307-86-1
• 分子量: 351.40
• MDL番号: MFCD18384955
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825294
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: ≥5 mg/mL
• 保管温度: 2-8°C
• SMILES記法: CC1(C)C(=O)C(C)(C)c2cc(ccc12)C(=O)Nc3ccc(cc3)C(O)=O
• InChI: 1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25)
• InChI Key: KFBPBWUZXBYJDG-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

BMS 753 is a very potent, specific agonist for RARa (Ki = 2 nM). BMS 753 does not display significant effects on RARg in reporter based assays, or in binding assays measuring displacement of labeled retinoic acid.

特徴および利点

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable