S5439

Src ヒト

≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged

• MDL番号: MFCD03458574
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• リコンビナント: expressed in baculovirus infected insect cells
• アッセイ: ≥80% (SDS-PAGE)
• 形状: buffered aqueous glycerol solution
• 分子量: 60 kDa
• 濃度: ~0.58 mg/mL protein (Bradford assay)
• UniProtアクセッション番号: P12931
• アプリケーション: cell analysis
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... SRC(6714)

詳細

詳細

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

アプリケーション

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

生物化学的／生理学的作用

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

単位の定義

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30°C.

物理的形状

50mM Tris溶液 (pH 7.5, 0.05mM EDTA, 1mM DTT, 100mM NaCl, 0.05%NP-40, 50%グリセロ-ル含有)。

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable