N9891

モノクロナール抗ネブリン マウス宿主抗体

clone NB2, ascites fluid

• 別名: Anti-AMC6, Anti-NEB177D, Anti-NEM2
• MDL番号: MFCD00164706
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: ascites fluid
• 抗体製品タイプ: primary antibodies
• クローン: NB2, monoclonal
• 分子量: antigen 500 kDa
• 含みます: 15 mM sodium azide
• 化学種の反応性: vertebrates, chicken
• テクニック: indirect immunofluorescence: 1:400 using frozen sections of animal skeletal muscle; western blot: suitable
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: chicken ... NEB(101748402)

詳細

詳細

Nebulin is a 700kDa protein which is expressed in skeletal muscles. It possesses 35 amino acid repeats and a C terminal serine-rich and SH3 domains.

Nebulin is also localized to cardiac muscle. Monoclonal Anti-Nebulin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

特異性

冷血脊椎動物からヒトまでさまざまな生物種の骨格筋に存在するネブリンを特定します。平滑筋や心筋のほか、非筋組織および培養細胞との交差反応はありません。間接免疫蛍光染色により、骨格筋切片の I 帯に存在するネブリンが特定されています。

免疫原

ニワトリ胸部ネブリン。

アプリケーション

Monoclonal Anti-Nebulin antibody produced in mouse has been used in:

• immunohistochemistry
• fluorescent immunostaining
• western blotting

生物化学的／生理学的作用

Nebulin associates with the Z-line and thin actin filament in a sarcomere. It may function as a regulator of sarcomere thin filament length. The protein also acts as a structural link between sarcomeres. Nebulin interacts with the capping protein CapZ and has a role in controlling the localization of actin filaments.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable