M6324

MART-1 (27-35)、ヒト

• 別名: Melan-A タンパク質 (27-35)、ヒト, T細胞 1 (27-35) 認識メラノーマ抗原、ヒト, 抗原 LB39-AA (27-35)、ヒト, 抗原 SK29-AA (27-35)、ヒト
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 形状: lyophilized powder
• 品質水準: 200
• 色: white
• 溶解性: water, double-distilled: soluble
• 保管温度: −20°C

詳細

Amino Acid Sequence

Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val

詳細

Melanoma-associated antigen recognized by T cells-1 (MART-1), also known as Melan-A, is encoded by the gene mapped to human chromosome 9p24.1. The encoded protein is a hydrophobic transmembrane protein. MART-1 is mainly expressed in skin and retinae melanocytes.

The peptide represents amino acids 27-35 of MART-1 protein that is the melanoma antigen recognized by T cells. This peptide mimics the natural epitope that is presented by T cells in humans with reactivity to melanoma cells.

T細胞によって認識されるメラノーマ抗原であるMART-1タンパク質のアミノ酸27～35を表すペプチドです。このペプチドは、メラノーマ細胞に対する反応性を有するヒトのT細胞によって提示される天然のエピトープを模倣しています。

生物化学的／生理学的作用

Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma.

物理的形状

凍結乾燥品(0.1% TFA水溶液)。

その他情報

Lyophilized from 0.1% TFA in H2O

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable